Buy Sofosbuvir And Velpatasvir Brands In India
Sofosbuvir Velpatasvir Buy Online, if the agreement on centralized supplies at the official level was not concluded, and the drug is not available in pharmacies? Only from the official Indian representative of the companies Natco and Mylan. Medixo Centre is such an official representative. We sell hepatitis C generics at the price of Indian companies. The medicine ordered from us will be delivered to you by courier service within a few days.
MyHep All is a combined DAA, a direct antiviral drug for the treatment of hepatitis C. This tool is a product of the Indian pharmaceutical company Mylan Pharmaceuticals (Mylan Pharmaceuticals). This is indicated on the packaging. In fact, the drug is produced by another company from India, Natco Pharma.
It is an experienced manufacturer of hepatitis C drugs in the form of licensed copies, generics, original drugs from the United States. The production of the drug is carried out at Natco factories. And Mylan packs it up and distributes it in India under his own name.
Where to buy Sofosbuvir and Velpatasvir (MyHep All) Online from India?
The medicine is available in the form of oval gray-green coated tablets for oral administration. The surface of the tablets is engraved: M on one side and SFV on the other.
The active substances Sofosbuvir and Velpatasvir are DAAs. Sofosbuvir MyHep inhibits viral nonstructural protein NS 5 B . As a result, the process of copying the RNA of the virus during its reproduction in hepatocytes and liver cells is disrupted.
Velpatasvir MyHep inhibits NS 5 A non-structural protein. This makes it difficult to copy RNA, and leads to the appearance of non-viable viral particles (virions). The resulting virions cannot penetrate into new hepatocytes.
By themselves, Sofosbuvir and Velpatasvir, taken on their own, do not always destroy the virus. But when they are combined, the key phases of viral reproduction are inhibited. The virus dies and 97-99% of patients recover.
MyHep All tablets in the amount of 28 pcs. are in a blue plastic jar with an aluminum mica neck and a screw cap. The can together with the instructions in English is placed inside a cardboard box.
On the can and on the box, basic information about the drug is displayed: name, manufacturer, active substances, recommendations for storage. The serial number, date of issue, and expiration date, Sofosbuvir Velpatasvir Cost in Indian rupees are also indicated here.
Indications and contraindications
Sofosbuvir, Velpatasvir treatment is indicated for hepatitis C caused by any known genotype of the hepatitis C virus. The drug is effective for chronic hepatitis C complicated by hepatic fibrosis or compensated cirrhosis. DAAs are indicated for those patients whose previous treatment with Interferon did not lead to recovery.
This remedy is not prescribed for lactating and pregnant women, as well as for persons under 18 years of age. If you are allergic to Sofosbuvir, Velpatasvir, and any excipient, taking pills is also contraindicated.
Take 1 tablet daily. 1 time regardless of food. But, so that there are no jumps in the concentration of active substances in the blood plasma, the tablets are taken at the same time of the day. The tablet is swallowed whole during administration, not crushed, not chewed, and washed down with a glass of water.
The duration of the course of treatment is 12 weeks. Treatment is extended to 24 weeks if the disease is caused by genotype 3 of the virus, and is complicated by compensated hepatic cirrhosis, or if a patient with genotype 3 has previously been treated with interferon without effect. But if Ribavirin is added to the DAA, then recovery occurs after 12 weeks.
The main side effects of DAA treatment are associated with digestive disorders: nausea, intermittent vomiting, abdominal pain, bloating, unstable stools. Patients complain of headache, dizziness, insomnia, irritability. As a rule, these effects are short-lived and do not require discontinuation of the medication.
Cancellation is required if hives, shortness of breath, and other signs of allergies appear. On Sofosbuvir, Velpatasvir, reviews indicate their good tolerance by most patients. But at the first signs of deterioration, you need to see a doctor.
Interaction with other medications
P-glycoprotein transport protein inducers reduce the level of DAA in the blood, and this negatively affects the effectiveness of treatment. These include:
- Phenytoin, Oscarbazepine, Carbamazepine
- Rifabutin, Rifampicin
- drugs based on Hypericum perforatum.
When combined with cardiac glycosides, the antiarrhythmic drug Amiodarone, dangerous cardiac arrhythmias can occur. The combination with warfarin and some other drugs that inhibit blood clotting can lead to bleeding.
Coating agents, as well as any drugs that reduce the acidity of the gastric environment, impair the absorption of Sofosbuvir with Velpatasvir. Therefore, at least 4 hours should elapse between the intake of these funds and the DAA.
Benefits of Sofosbuvir and Velpatasvir generic Brands in India
MyH ep All is a generic tablet of Epclus from the American company Gilead Sciences. The active substances, their content, effectiveness, the mode of administration of Epclusa and Myhep All are all identical. After all, their production technology is also the same.
A few years ago, Gilead licensed Natco to release the generic Epclusa, an original priced at tens of thousands of dollars. At the same time, the Epclusa Cost for the produced Mylan Sofosbuvir, Velpatasvir in India is only a few tens of thousands of dollars.