Soranib 200 mg (Sorafenib)
Soranib 200 mg is prescribed for the treatment of advanced kidney or liver cancers. This anti-cancer medicines also used for the treatment of thyroid cancers. It is manufactured by Cipla Ltd. A strength of the drug used for commercial purposes is 200mg. Each tablet contains 200 mg of “Sorafenib Tosylate”. It is available in a pack of 120 tablets. Soranib 200 mg is a prescription drug implying that it can be purchased by patients who carry a valid prescription of a registered medical practitioner.
Soranib 200 mg tablet is used to treat liver cancer, kidney cancer. This medicine is used during chemotherapy. It interferes with the growth as well as the spread of cancer cells in the human body.
Mechanism of Action:
The drug is a kinase inhibitor and it decreases the number of tumour cell proliferation in the body. Sorafenib 200 mg was shown to inhibit more than one intracellular (BRAF, c-CRAF, and mutant BRAF) kinesis. It was shown to inhibit more than one cell surface kinesis (KIT, RET, FLT- 3, RET/PTC, VEGFR- 2, VEGFR-1, VEGFR- 3, and PDGFR-ß). Researchers are of the opinion that many of these kinesis are involved in tumour cell signaling, apoptosis, and angiogenesis. Sorafenib slowed down tumour growth of RCC, HCC, and DTC human tumor xenografts in immune-compromised mice. Sorafenib treatment caused reductions in tumor angiogenesis in models of RCC and HCC. Observations reveal that Sorafenib treatment caused an increase in tumor apoptosis in models of RCC, HCC, and DTC.
Dosage and Administration:
The recommended daily dose of Soranib tablets is 400 mg (i.e. 2 x 200 mg tablets) taken two times daily without food (at least an hour before or 2 hours after a meal).
Some of the common side effects of Soranib 200 mg tablets include:
- mouth sores
- coughing up blood or vomit
- black, bloody, or tarry stools
- pale skin,
- feeling short of breath
- rapid heart rate,
- trouble concentrating
- easy bruising,
- unusual bleeding (nose, mouth, vagina, or rectum),
- chest pain or heavy feeling,
- general ill feeling
- a dry cough, wheezing
- rapid weight gain,
- sudden numbness or weakness,
- sudden weight loss,
- increased appetite,
- trouble sleeping,
- increased bowel movements,
- feeling nervous or anxious,
- swelling in the neck (goiter)
- Very high blood pressure (a severe headache, blurred vision, buzzing in your ears, confusion, anxiety, seizure, uneven heartbeats)
- severe skin reaction,
- a sore throat
Tell the doctor if you have any of the following problems:
- Kidney or liver problems besides cancer
- A bleeding or blood clotting disorder like haemophilia
- High blood pressure or hypertension
- Heart disease
- A history of stroke
- A history of heart attack
- It is harmful to take this medicine in times of pregnancy.
Soranib 200 mg price in India
Soranib price is quite affordable for us. You can get Soranib 200 mg is available at the 50% discounted price offered by Medixo Centre. If one wants to purchase the drug then one should check the “Nexavar cost” and then “buy soranib online”.
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