Ledifos tablets (Ledipasvir & Sofosbuvir)
Ledifos is a Hepatitis C medicine with the combination of a couple of drugs named Ledipasvir 90mg and Sofosbuvir 400mg. The manufacturer of this Hepatitis C medicine is Hetero Healthcare Limited. Ledifos tablets are actually used for the successful treatment of Chronic HCV (Hepatitis C Virus) with genotype 6, 5, 4, or 1 infection respectively. This Hepatitis C medicine is a fixed-dose-type tablet with the combination of Ledipasvir 90mg + Sofosbuvir 400mg for superior oral administration.
Ledifos is a perfect blend of two types of drugs, used to treat chronic HCV. Every Ledifos tablets are a combination of Ledipasvir 90mg as well as Sofosbuvir 400mg, Both these drugs work as good antiviral agents that treat the HCV complications by interfering securely with the additional imitation of HCV. Also used in the treatment of patients suffering from Genotype 1 HCV.
Uses & Administration
Ledifos tablets come in the bottle pack of 28 tablets. Each tablet consists of Ledipasvir & Sofosbuvir as active ingredients. The patient needs to swallow a tablet with water.
The healthcare professional will prescribe the dosage of Ledifos for the patients, according to the severity of their diseases. It’s highly recommended that patients follow the prescribed dosage at any precise time during the day and maintain that time. You need to take Ledifos tablets for the advised time duration by your physician.
Mechanisms of Action
- Ledipasvir: Ledipasvir is an HCV inhibitor, which highly targets the HCV NS5A protein because it’s very important for the RNA replication as well as HCV vision assembly.
- Sofosbuvir: Sofosbuvir is a pan-genotypic inhibitor that targets HCV NS5B RNA polymerase that is very important for viral reproduction. Its nucleotide pro-drug endures intracellular metabolism for creating pharmacologically working Uridine Analog Triphosphate, which is included in HCV RNA through NS5B polymerase as well as works as the chain terminator.
- Ledifos tablets must be taken under the strict supervision of a Hepatologist only.
- The length of the treatment for Ledifos may differ from the period of 8 weeks to 24 weeks according to the body condition.
- The patients should be a minimum of 18 years old to take this Hepatitis C medicine.
- You should take it orally with a glass of water.
- You shouldn’t stop taking this tablet until recommended by your physician.
Benefits of Ledifos
There are many benefits of Ledifos tablets. Just go through the benefits given below.
- Harvoni is the international brand name for this drug that provides effective treatment against Chronic Hepatitis C with successful results of 94 to 99%.
- It reduces the amount of HCVs in the human body through the protecting spread of HCV in the body. This medicine is highly recommended for the early-stage treatment as well as repeat treatment of patients that are accompanied by Chronic HCV infection’s Genotypes 1,4, 5, or 6 respectively.
- Mainly work for decreasing Hepatitis C virus from the body as well as also help the immune system for fighting against the infections and help the liver in the easy recovery.
- Ledipasvir & Sofosbuvir drugs are mainly used for treating chronic hepatitis C virus in most patients.
- Ledipasvir 90mg, an NS5A inhibitor as well as Sofosbuvir 400mg, the nucleotide inhibitor for RNA polymerase.
- This drug helps protect Chronic HCV infection in the body through weakening that virus as well as inhibiting the reproduction or replication.
Ledifos Side Effects
Ledifos tablets have a much better side-effects profile than previous interferon-based treatments. The most general side effects of Ledifos medicine as given in the clinical studies include tiredness, headache, diarrhea, insomnia, loss of appetite and nausea.
Severe side effects might show allergic reaction signs like rashes, hives, difficulty in breathing, excessive itching, mouth swelling, tightness in the chest and cardiovascular problems. In case, you notice one of these side effects, immediately go for medical attention.
Ledifos Tablets have an extremely high cure rate so; it’s a perfect treatment for the majority of Hepatitis C patients. However, there are some situations in which you shouldn’t take sofosbuvir and ledipasvir:
- Don’t take Ledifos if you are suffering from the allergy of its active ingredients Ledipasvir & Sofosbuvir.
- Do not use Ledifos if you are taking any other medicines containing Sofosbuvir.
- Don’t use Ledifos if you are taking any medicines having drugs like Cobicistat, Emtricitabine, Elvitegravir, Carbamazepine, Rifapentine, Rosuvastatin, Tenofovir, Oxcarbazepine, Rifabutin, Phenytoin, Phenobarbital, Simeprevir, Rifampin, Ritonavir or Tipranavir.
There are a few other conditions that you should discuss with your doctor. It’s not necessary that these conditions make you stop taking; however, you still need to get monitored closely.
Inform your physician in case of any of the following terms applies to you:
- If you are breastfeeding, pregnant or planning to have pregnancy
- You are presently taking any prescribed or non-prescribed drugs, dietary supplements or herbal preparations
- If you are suffering from any kidney or liver problems
- You have allergies to any food, substances or medicines
Generic Harvoni cost in India
Ledipasvir and Sofosbuvir plays an important role if you want to buy Ledifos online, Therefore you can examine this important factor before you buy The Ledifos price in India is 99% times cheaper than the original Generic Harvoni cost in India“. At Medixo Centre, we help you get sofosbuvir and ledipasvir online at reasonable prices!
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