Ledipasvir and Sofosbuvir tablets are extensively used in the treatment of Hepatitis C and also the genotypes 1, 4, 5, and 6 along with chronic Hepatitis C. This medicine is an antiviral regimen and is the first medicine to have an FDA approved interferon. A ribavirin-free regimen in the treatment of Hepatitis C.
Patients diagnosed with genotype 1A can be given the combination of Ledipasvir and Sofosbuvir without ribavirin. However, it is exceptional for the ones who are cirrhotic. The NS5B-NS5A inhibitor combination is known to have cured a lot of patients diagnosed with decompensated cirrhosis. This medicine is manufactured by Gilead Sciences. The Ledipasvir 90mg and Sofosbuvir 400mg are the dosages that can be given to the patients.
This medicine is effectively used in the treatment of chronic hepatitis and also the genotypes 1, 4, 5 and 6. The medicine can be used for 8-12 weeks under proper diagnosis and supervision by a medical practitioner. Also, the brand Harvoni manufactures the best medicines which are quite effective for patients. Who are treatment-naïve and those who are not suffering from cirrhosis can be treated for 8 to 12 weeks after proper clinical trials and observations.
However, “Ledipasvir and Sofosbuvir tablets” are recommended to be given to the patients only under proper medical supervision and diagnosis. It would always be a better option to seek advice from a medical expert before getting into any sort of treatment. You can also choose to buy Ledipasvir and Sofosbuvir online as well.
Mechanism of action of Ledipasvir and Sofosbuvir
Since Ledipasvir is a powerful inhibitor of HCV NS5A, it is one of the best viral phosphoprotein which has a significant role in viral replication. It also helps in the assembly and secretion of the virus. The key enzyme present is a nucleotide analog inhibitor of hepatitis C virus (NS5B polymerase)plays a vital role in killing the hepatitis C causing virus. The HCV RNA polymerase supports the triphosphate form of Sofosbuvir (GS-461203) into the RNA primer strand and this result in the termination of the viral chain. The “Ledipasvir and Sofosbuvir cost” is affordable and this makes the treatment easier for patients suffering from Hepatitis C.
Fortunately, the patients who have undergone the trials of the Ledipasvir and Sofosbuvir tablets have been quite tolerant and there aren’t many side-effects found with the usage of these medicines. Hence, this medicine is found to be one of the most tolerable ones in the treatment of Hepatitis C causing virus. Also, Ledipasvir and Sofosbuvir price in India is affordable hence; it is widely used in the treatment of Hepatitis C.
The only reported side-effects with the usage of our headache and nausea.
There are no other side-effects reported with the usage of this medicine as this can be used without ribavirin as well.