Sovaldi 400mg, also known as Sofosbuvir is one of the antiviral medicines that are used extensively to treat the conditions of hepatitis C. The Hepatitis C causing virus is known to have reduced drastically with the usage of this medicine. The Hepatitis C causing virus does not multiply in the body when Sofosbuvir 400mg is taken properly under a medical practitioner’s guidance.
Sovaldi Sofosbuvir 400 mg is always given in combination with the other medicines in order to treat Hepatitis C and the virus causing Hepatitis C. A lot of patients suffering from Hepatitis C Medicine have been prescribed with this medicine. This medicine is usually given to children above 12 years and also adults. It is generally not prescribed to infants or children aged below 12.
Sovaldi 400mg should always be used after consulting a medical practitioner as this medicine is used in the treatment of specific genotypes of Hepatitis C and it can be given to a very few people. Hence, a proper consultation and a thorough check-up are required before taking this medicine.
This medicine can also be taken by patients who are diagnosed with liver disorders like liver cancer, liver transplant and also the ones who are affected by Anti HIV Medicines. However, this medicine is definitely not the right one for treating patients affected by AIDS. This medicine is usually used with ribavirin which may or may not have the peg interferon alfa component in it for effective results. Sovaldi 400mg should never be used as a standalone medicine at any cost as it may have a lot of adverse effects.
A dosage of Sovaldi 400 mg
For Adults suffering from Chronic Hepatitis C
A dosage of 400 mg is usually recommended once a day for adults.
The Regimen and the duration of the therapy is as recommended below
For Genotype 1 or 4 – Sofosbuvir along with peginterferon alfa and ribavirin should be prescribed for 12 weeks
For Genotype 2 – Sofosbuvir should be given along with ribavirin for 12 weeks for effective results
For Genotype 3- Sofosbuvir along with ribavirin in combination would usually be prescribed for 24 weeks
For patients who are diagnosed with Hepatocellular carcinoma awaiting liver transplantation, Sovaldi 400mg along with ribavirin 200mg capsules would usually be prescribed for 48 weeks.
For Genotype 1, 4: The dosages recommended would usually be for patients who are either therapy-naïve and usually for the ones without cirrhosis or with compensated cirrhosis (Child-Pugh A).
Genotype 2, 3: The line of treatment is recommended for patients who are yet to undergo or would have already exposed to any sort of treatments related to compensated cirrhosis or without cirrhosis (Child-Pugh A).
Therapy-experienced patients have usually shown symptoms of failure during an interferon-based regimen which would be prescribed with or without ribavirin.
The dose recommendations are different for different genotypes and usually for genotypes 1, 2, 3, or 4 this treatment is generally given to patients infected with HCV/HIV-1-coinfected.
Consulting a medical practitioner for both ribavirin and peginterferon alfa about the manufacturer details is a must before taking this medicine. This is mandatory for all the genotypes, however; it is really crucial for the genotypes 1 and 4 and it has to be done without fail.
Sovaldi 400mg along with ribavirin can be given to patients with genotype 1 infection who are not interferon-based regimen friendly. This treatment is usually recommended for 24 weeks and this is again dependant on the condition of the patients.
The treatment is recommended for patients suffering from hepatocellular carcinoma awaiting liver transplantation in order to avoid any further complications after liver transplant.
Usage of Sovaldi 400 mg
This medicine should always be given in combination with other antiviral medicines for treating chronic HCV infections.
This drug should always be given in combination with Pegylated interferon and ribavirin if the patients are diagnosed with genotype 1 or 4 infections without cirrhosis or with compensated cirrhosis.
This drug should always be given in combination with ribavirin for patients diagnosed with genotype 2 or 3 infections without cirrhosis or with compensated cirrhosis.
Side effects of using Sovaldi 400 mg
A lot of patients have complained of difficulty in breathing, swelling of the face, lips and other parts of the body.
It is always recommended to seek medical assistance on a case of stomach aches, discoloration or dark color urine or stools, symptoms of jaundice, nausea, loss of appetite, and drop in pulse rate, fatigue, sweating, fever, cold, cough, lack of sleep, anemiaand memory related problems.
Please avoid taking Sovaldi along with amiodarone as it may have adverse effects on the heart.
Prevention while using Sovaldi 400 mg You need to remember that by just being under treatment of this medicine would never cease you from transmitting the HCV to someone else. Hence, avoid indulging in sexual intercourse, sharing blades, razors or any other things that can come in direct contact with skin.
Get a thorough check-up of all the parts of the body including the blood and stools before taking this medicine.
Keep a constant check on the blood tests during the treatment.
Always take this medicine as a whole and it can be taken with or without food
People diagnosed with Hepatitis B should never take this medicine without proper guidance as it can worsen the condition.
Pregnant ladies, would-be moms, and lactating mothers should avoid the usage of this medicine.
Availability of generic Sovaldi online
The price for Sovaldi was $84000 and it was ridiculously high. In this situation, the generic medicine was introduced at the price of $1000 per treatment. This medicine is available online hence patients diagnosed with hepatitis C can buy Sovaldi 400 mg online too. Since this medicine is available both in the USA and India people can parallel check the Sovaldi cost in USA and Sovaldi cost in India as well. It is quite affordable hence; a lot of doctors these days recommend this medicine to their patients. In case if the same medicine is not available, you could always check with your doctor and buy generic Sovaldi online.